U.S. equity marketsÂ ended the session mixed after New York City Mayor Bill de Blasio warned the city could see a full shutdown in the weeks ahead due to a surge in COVID-19 infections and as OPEC cut its oil demand forecast.
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“Weâ€™re seeing the kind of level of infection with the coronavirus we havenâ€™t seen since May and we have got to stop that momentum â€“Â or elseÂ our hospital system will be threatened,” de Blasio told CNN. Separately,Â Boston Mayor Marty Walsh announced the city is rolling back to Phase 2, Step 2 effective Wednesday, which will closeÂ gyms and fitness centers, along with theaters and museums, for around threeÂ weeks.
The Dow Jones Industrial Average ended down over 186 points or 0.62%,Â paring an early gain of as much as 270 points that came as the first batch of COVID-19 vaccines were delivered and as bipartisanÂ stimulus deal talks showedÂ signs of progress.
The S&P 500 also fell, ending 0.44% lower as energy stocks tumbledÂ after OPEC trimmed its 2021 demand forecast by 350,000 barrels per day.Â The cartel sees demand rising by 5.9 million bpd next year to 95.89 million.
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The tech-heavyÂ Nasdaq CompositeÂ outperformed,Â rising 0.5%,Â as stay-ay-home stocks like Zoom Technologies pared their early losses.
Tesla Inc., which will be added to the S&P 500 on Friday, was among the index’s leaders.
In vaccine news, a health care worker in New York state on Monday became the first American to receive theÂ Pfizer/BioNTech COVID-19 immunization.
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The vaccine will be delivered by FedEx Corp. to 145 U.S. hospitals Monday, followed by another 425 on Tuesday and 66 on Wednesday.
Health and Human Services Secretary Alex Azar told FOX Business 100 million people could be vaccinated by February.
TheÂ rollout comes amid chatter thatÂ negotiations surrounding a $900 billion COVID-19 relief package could restart after President Trump signed a bill that temporarily funds the government.
In mergers and acquisitions, British drugmaker AstraZeneca PLCÂ agreed to buy U.S. biotech Alexion Pharmaceuticals for $39 billion cash and stock. Alexion shareholders will receive a 45% premium to Fridayâ€™s closing price.
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Private-equity firm Vista Partners agreed to buy learning-software company Pluralsight Inc. for $3.5 billion cash, or a 25% premium to where shares settled on Friday.
Electronic Arts Inc. swooped in to buy U.K.-based racing game developer Codemasters in a $1.4 billion deal a month after rival Take-Two Interactive struck a $971 million agreement.
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Elsewhere, Virgin Galactic Inc. shares were sharply lower after the companyâ€™s test flight conducted on Saturday failed to reach space as planned. The company said a rocket motor did not fire due to the ignition sequence not completing.
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Looking at commodities, West Texas Intermediate crude, in a choppy session, rose 0.42 cents to $46.99Â per barrel, while gold slid $11.10 to $1,828.70 an ounce.
European markets were mixed with Germanyâ€™s DAX 40 climbing 0.83%, Franceâ€™s CAC 30 gaining 0.37% and Britainâ€™s FTSE 100 falling up 0.23%.
In Asia, Hong Kongâ€™s Hang Seng index slipped 0.44% while Japanâ€™s Nikkei gained 0.3% and Chinaâ€™s Shanghai Composite rallied 0.66%.